Lovable sarcastic antihero Deadpool (Ryan Reynolds) takes the audience back in time, when he figuratively and literally “took the guns out of the hands of criminals.” Unfortunately, he neglected to slaughter one bad meth boss (Thayr Harris). This mistake comes back to haunt him. Deadpool falls into a depression that no giant, comical bag of cocaine can fix.
Deadpool ends up becoming a reluctant “X-Man in training,” where he reunites with some familiar characters and meets Russell (Julian Dennison), a child mutant with anger issues who is in need of saving from Cable (Josh Brolin), a mysterious time traveler. In order to fight again this foe, Deadpool recruits a team, dubbed the X-Force, to take him on.